Ascites as the major manifestation of systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Hematologic manifestation of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. The most common hematologic finding is anemia, leukopenia, thrombocytopenia and secondary antiphospholipid syndrome with recurrent abortion and thrombosis. The autoimmune fibrosis of bone marrow is another manifestation of autoimmune disease especially SLE, that must be correctly differentiated from primary myelofibrosis.
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The pathogenesis of systemic lupus erythematosus (SLE) is influenced by both genetic factors and epigenetic modifications; the latter is a result of exposure to various environmental factors. Epigenetic modifications affect gene expression and alter cellular functions without modifying the genomic sequences. CpG-DNA methylation, histone modifications, and miRNAs are the main epigenetic factors ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1976
ISSN: 0004-3591,1529-0131
DOI: 10.1002/1529-0131(197607/08)19:4<782::aid-art1780190421>3.0.co;2-i